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Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … Human protein C ... Protein C human ... Protein C concentrate …
Matched Name: … Protein C
Matched Description: … A lack of protein C in the body would lead to unchecked coagulation activation, resulting in thrombin ... of excessive procoagulant responses to activating stimuli. ... in the presence of its cofactor protein S. …
Matched Categories: … protein C
Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as Pranactin-Citric) for the detection of Helicobacter pylori infections. H pylori is a common stomach bacteria that has been...
Approved
Matched Synonyms: … Urea 13 C ... Urea C 13 ... Urea, C-13 …
Matched Name: … Urea C-13 …
Matched Description: … As the urease enzyme is not present in mammalian cells, the presence of urease (and the products of urea ... H pylori is a common stomach bacteria that has been linked to a variety of upper gastrointestinal disorders ... The Urea Breath Test is based on the ability of the H. pylori enzyme urease to cleave urea into ammonia …
Matched Products: … Helicobacter Test Infai for Children Of The Age 3-11 ... HELICOBACTER TEST INFAI- UREA 13 C ... HELICOBACTER TEST INFAI (C-URE) 75 MG 1 SISE …
Equine Botulinum Neurotoxin G Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype G. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes G in...
Approved
Experimental
Investigational
Matched Synonyms: … Botulinum Neurotoxin G immune FAB2 (equine) ... BOTULINUM NEUROTOXIN G IMMUNE FAB2, EQUINE …
Matched Name: … Equine Botulinum Neurotoxin G Immune FAB2 …
Matched Description: … exposure to botulinum neurotoxin serotypes G in adults and pediatric patients. ... Equine Botulinum Neurotoxin G Immune FAB2 is composed of a mixture of immune globulin fragments purified ... from plasma of horses that were previously immunized with botulinum toxin serotype G. …
Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging.
Approved
Matched Synonyms: … (11)C-choline …
Matched Name: … Choline C-11 …
Matched Description: … Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging ... of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized …
Matched Products: … Choline C 11 …
Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup C. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C.
Approved
Experimental
Investigational
Matched Synonyms: … Meningococcal group C polysaccharide ... Meningococcal polysaccharide antigen group C ... Neisseria meningitidis group C capsular polysaccharide antigen …
Matched Name: … Meningococcal polysaccharide vaccine group C
Matched Description: … from *Neisseria meningitidis* serogroup C. ... Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified ... administered as an active immunization against the invasive meningococcal disease caused by the serogroup C. …
Matched Mixtures name: … Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze ... MENACTRA 0,5 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 5 ADET ... Neisvac-C
Matched Products: … NEISVAC-C
Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and premature death most commonly due to respiratory...
Approved
Investigational
Matched Synonyms: … (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G ... ),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl)-1-piperazinyl)-N,N-dimethylphosphonamidate …
Matched Description: … to exon 51 skipping. ... [A244930] It is caused by loss-of-function mutations in the DMD gene coding for dystrophin, an essential ... (DMD) in patients with a confirmed mutation of the DMD gene, which codes for dystrophin, that is amenable …
Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for in vivo diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxetan) in preparations used for radioimmunotherapy procedures. It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in...
Approved
Matched Synonyms: … Indium chloride In-111 ... Indium In 111 chloride ... Indium In 111m chloride …
Matched Name: … Indium In-111 chloride …
Matched Iupac: … trichloro(¹¹¹In)indigane …
Matched Description: … It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI. ... Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint ... used for _in vivo_ diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxetan) in
Matched Mixtures name: … INDIO (IN-111) DTPA CURIUM NETHERLANDS ... INDIO (111-IN) OSSINA CURIUM NETHERLANDS …
Matched Products: … Indium In 111 Chloride ... INDIO (111-IN) CLORURO CURIUM NETHERLANDS …
Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.
Approved
Matched Synonyms: … Indium In 111 pentetate ... Indium In-111 pentetate …
Matched Name: … Indium In-111 pentetate …
Matched Iupac: … (111In)indium(3+) ion 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetate …
Matched Description: … Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the ... Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography …
Matched Salts name: … Indium In-111 pentetate disodium …
Matched Products: … In-111 DTPA ... Indium DTPA In 111 …
Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of autologous leukocytes. It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. Indium-111 decays by isomeric transition and electron capture to cadmium-111, emitting a gamma ray that can be detected with a gamma ray...
Approved
Matched Synonyms: … In-111 oxyquinoline ... Indium In-111 oxine ... Indium (111 In) oxyquinoline …
Matched Name: … Indium In-111 oxyquinoline …
Matched Iupac: … (111In)indium(3+) ion tris(quinolin-8-olate) …
Matched Description: … It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. ... It is therefore useful in nuclear medicine, and is used in the labeling of leukocytes for localization ... Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of
Matched Products: … Indium In 111 Oxyquinoline ... Indium in 111 Oxyquinoline …
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … matrix proteins, all of which are known to be involved in wound repair. ... [L35505] Stratagraft was in the early stages of development as far back as 2009[A237275] and was granted ... full FDA approval in June 2021. …
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … [A253277] Several serogroups of _N. meningitidis_ - A, B, C, Y, and W-135 - known to cause meningococcal ... _ CRM197 protein carrier, resulting in four drug substances contained in each dose of vaccine. ... the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia …
Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Synonyms: … Mitocin-C ... Mitomycin C ... Mitomycin-C
Matched Description: … of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper Tract ... [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety ... Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MUTAMYCIN ©INYECTABLE 5 MG. ... MITOMYCIN C ... MITOMYCIN-C KYOWA FOR INJECTION 2 mg/vial …
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched International brands: … White-C
Matched Synonyms: … G-CSF …
Matched Description: … Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood. ... G-CSF and has an N-terminal methionine added in the sequence for expression in _E. ... It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous …
Matched Products: … FRAVEN 30 MIU/0,5 ML IV INFUZYON/SC ENJEKSIYON ICIN COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 3 ADET ... ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... Zarzio 48 MU/0.5 ml solution for injection or infusion in pre-filled syringe …
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … (T,G)-A-L …
Matched Description: … myelin antigen involved in the development of multiple sclerosis (MS), to induce experimental autoimmune ... [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. ... , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. …
Matched Products: … Copaxone 20 mg/ml Injektionslösung in einer Fertigspritze ... Copaxone 40 mg/ml Injektionslösung in einer Fertigspritze ... Copaxobene 20 mg/ml Injektionslösung in einer Fertigspritze …
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Approved
Matched Synonyms: … G-ol …
Matched Description: … A polyhydric alcohol with about half the sweetness of sucrose. ... It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for …
Matched Mixtures name: … Cystosol W 3% Hexitols ... Char-flo With Sorbitol - Sus ... MICROLAX LAVMAN, 10 G
Matched Categories: … Compounds used in a research, industrial, or household setting …
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP ... IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP ... 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY …
Matched Description: … Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed ... It works to recruit CD3-expressing T cells to GPRC5D-expressing multiple myeloma cells to induce T-cell–mediated ... CD3 T-cell engager. …
Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Synonyms: … 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea ... 1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 3-[(3aR,6aS)-octahydrocyclopenta[c]pyrrol-2-yl]-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination ... β cells of the pancreas to release insulin. ... It has been classified differently according to its drug properties in which based on its chemical structure …
Matched Categories: … Drugs Used in Diabetes ... combinations of sulfonamides …
Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.
Approved
Investigational
Matched Synonyms: … N(G)-Methylarginine ... N(G)-Monomethyl-L-arginine …
Matched Iupac: … (2S)-2-amino-5-(N'-methylcarbamimidamido)pentanoic acid …
Matched Description: … Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 …
Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia[FDA Label] . Omega-3-acid ethyl esters are currently marketed in the US, EU,...
Approved
Investigational
Matched Synonyms: … Omega-3-acid ethyl esters ... Omega-3 fatty acid ethyl esters …
Matched Name: … Omega-3-acid ethyl esters …
Matched Description: … and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower ... Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand ... Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) …
Matched Mixtures name: … Omega-3 Well Pack ... Omega-3 Well Pack ... Omega-3 Rx Complete …
Matched Categories: … Fatty Acids, Omega-3
Matched Products: … OMEGA 3 DOC ... OMEGA 3 TEVA ... OMEGA 3 MYLAN …
Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis and called collectively gramicidin D. Gramcidins are 15 residue peptides with alternating D and L amino...
Approved
Matched Synonyms: … Gramicidin C
Matched Iupac: … yl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl ... }-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylpropyl ... 1S)-1-{[(1R)-1-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1R)-1-{[(1S)-1-[(2-hydroxyethyl)carbamoyl]-2-(1H-indol-3- ... ]carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]carbamoyl}ethyl]-2-{2-[(2S)-2-formamido-3-methylbutanamido …
Matched Description: … hydrophobic interior of the cellular lipid bilayer to form a β-helix. ... Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making ... some Gram-negative organisms, Gramicidin D is used primarily as a topical antibiotic and is also found in
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D&C Yellow No. 7 ... D and C Yellow No. 7 ... 3',6'-dihydroxyfluoran …
Matched Iupac: … 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one …
Matched Description: … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline ... It has been approved by FDA for use in externally applied drugs and cosmetics. ... medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries …
Matched Categories: … Diagnostic Uses of Chemicals ... Heterocyclic Compounds, 3-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … FLUSİBLE 500 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... OCUBELLA 500 MG/5 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Approved
Nutraceutical
Matched Synonyms: … Vitamin C magnesium salt …
Matched Iupac: … magnesium(2+) bis((2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl …
Matched Iupac: … )-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl ... N-[(1S,2R,3R,4S,5R,6R)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl …
Matched Description: … In humans, the use of dihydrostreptomycin has been associated with ototoxicity. ... The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate …
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Synonyms: … Autologous CD34+ cells encoding βA-T87Q-Globin gene
Matched Description: … [L42940] β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a ... lentiviral vector gene therapy available in the U.S. for the treatment of people with β-thalassemia. ... Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … -1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester ... -1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester ... [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho ... [2,3-c]furan-6-yl]carbamate …
Matched Description: … indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history ... of myocardial infarction (MI) or with peripheral arterial disease (PAD). ... Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) …
Displaying drugs 1 - 25 of 15262 in total